Pachycarpine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Pachycarpine是从金雀花中提取的天然产物，是一种钠通道阻滞剂和1a类抗心律失常药。

Pachycarpine is a natural product extracted from scotch broom is a sodium channel blocker and a class 1a antiarrhythmic agent.(In Vitro):(+)-Sparteine (2 μM) reduces the ACh-induced current caused by activation of nicotinic AChRs in a voltage-independent manner. (+)-Sparteine (5, 10 μM) reduces the amplitude of the excitatory postsynaptic current (EPSC) and the time constant of the EPSC decay.

(+)-Sparteine (2 μM) reduces the ACh-induced current caused by activation of nicotinic AChRs in a voltage-independent manner. (+)-Sparteine (5, 10 μM) reduces the amplitude of the excitatory postsynaptic current (EPSC) and the time constant of the EPSC decay.

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(+)-Sparteine

Endocrinology/Hormones

AChR

AChR

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492-08-0

234.38

C15H26N2

>98% (HPLC)

H2O:2.86 mg/mL (12.20 mM; Need ultrasonic)

C1CCN2C[C@H]3C[C@H](CN4CCCC[C@H]34)[C@@H]2C1

(7R-(7alpha7aalpha14alpha14abeta))-Dodecahydro-714-methano-2H6H-dipyrido (12-a:1'2'-e)(15)diazocine

(-20℃)

With Ice Pack

≥ 2 years