Deltorphin I(TFA)

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Deltorphin I(TFA) 是 δ-阿片受体的激动剂。

Deltorphin I(TFA) is an agonist of δ-opioid receptor.

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Twice daily administration of Deltorphin I (20μg/mouse) for 4 days produces tolerance to Deltorphin I analgesia, as shown by the decrease in the analgesic response. The peak analgesic response to Deltorphin I (20 μg/mouse) at 10 min after injections is decreased from 8.36±0.28 s (the 1st day) to 4.53±0.14 s (the 4th day) markedly. Concurrent treatment of Melatonin (0.5, 1 and 2.5 mg/kg) and Deltorphin I (20 μg/mouse) twice daily for 4 days can attenuate the tolerance to Deltorphin I analgesia (P<0.05, <0.05 and <0.05), and this effect is dose dependent.

Deltorphin 1 | Deltorphin C

Endocrinology/Hormones

Opioid Receptor

δ-opioid receptor

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122752-15-2

768.86

C37H52N8O10

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (32.52 mM)

CC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)NCC(N)=O)C(C)C

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(-20℃)

With Ice Pack

≥ 2 years