Hexa-D-arginine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Hexa-D-arginine 是一种弗林蛋白酶抑制剂，可阻断体内铜绿假单胞菌外毒素 A 的激活。

Hexa-D-arginine?is an inhibitor of furinblocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.

Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic.

Administration of Hexa-D-arginine (0.1, 1, or 10 nM) to Pseudomonas aeruginosa exotoxin A (PEA)-treated mice (6-week-old FVB and 129/Sv mice) significantly improves their survival rate and also decreases circulating levels of TNF-α.

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Others

Other Targets

furin

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673202-67-0

954.14

C36H75N25O6

>98% (HPLC)

In Vitro:?H2O : 50 mg/mL (52.40 mM)

C(C[C@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N)N)CN=C(N)N

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(-20℃)

With Ice Pack

≥ 2 years