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Uridine triphosphate
CAS No. 63-39-8
Uridine triphosphate ( UTP | Uridine 5'-triphosphate )
产品货号. M20977 CAS No. 63-39-8
三磷酸尿苷通过激活 P2Y2 受体来增加人癌性胰管上皮细胞的增殖。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥283 | 有现货 |
|
| 10MG | ￥468 | 有现货 |
|
| 25MG | ￥701 | 有现货 |
|
| 50MG | ￥909 | 有现货 |
|
| 100MG | ￥1332 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Uridine triphosphate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述三磷酸尿苷通过激活 P2Y2 受体来增加人癌性胰管上皮细胞的增殖。
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产品描述Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
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体外实验Western Blot Analysis Cell Line:RT4-D6P2T cells Concentration:250 μM Incubation Time:5 min, 45 min, 2 h, 6 h, 12 h, 24 h, 48 h Result:Induces biphasic MAPK phosphorylation.
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体内实验Animal Model:Male Wistar rats (250-300 g; 2-3 months) with myocardial infarction (MI)Dosage:0.44 μg/kg 30 min before MI, and 4.4 μg/kg i.v. 24 h prior to MI.Administration:i.v.; once Result:Reduced infarct size and improves rat heart function after myocardial infarct.
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同义词UTP | Uridine 5'-triphosphate
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通路Others
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靶点Other Targets
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受体Others
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研究领域Metabolic Disease
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适应症Bronchitis; Cystic fibrosis; Lung Cancer; Primary ciliary dyskinesia
化学信息
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CAS Number63-39-8
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分子量484.14
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分子式C9H15N2O15P3
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纯度>98% (HPLC)
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溶解度H2O:150 mg/mL (309.83 mM)
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SMILESO=c1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)[nH]1
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化学全称(((2R3S4R5R)-5-(24-dioxo-34-dihydropyrimidin-1(2H)-yl)-34-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Choi J H Ji Y G Lee D H . Uridine Triphosphate Increases Proliferation of Human Cancerous Pancreatic Duct Epithelial Cells by Activating P2Y2 Receptor[J]. Pancreas 2013 42(4):680-686.
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