2-hydroxy Flutamide
CAS No. 52806-53-8
2-hydroxy Flutamide ( —— )
产品货号. M20966 CAS No. 52806-53-8
2-羟基 Flutamide 竞争性抑制雄激素受体 (AR),用于治疗前列腺癌。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥467 | 有现货 |
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| 10MG | ¥782 | 有现货 |
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| 25MG | ¥1469 | 有现货 |
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| 50MG | ¥2213 | 有现货 |
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| 100MG | ¥3195 | 有现货 |
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| 200MG | ¥4464 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥459 | 有现货 |
|
生物学信息
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产品名称2-hydroxy Flutamide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述2-羟基 Flutamide 竞争性抑制雄激素受体 (AR),用于治疗前列腺癌。
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产品描述2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR)?for the treatment of prostate cancer.
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体外实验——
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体内实验——
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同义词——
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通路Endocrinology/Hormones
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靶点Androgen Receptor (AR)
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受体Androgen Receptor
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研究领域Cancer
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适应症Prostate Cancer
化学信息
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CAS Number52806-53-8
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分子量292.21
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分子式C11H11F3N2O4
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纯度>98% (HPLC)
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溶解度DMSO:25mg/ml(85.5 mM)
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SMILESCC(C)(O)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1
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化学全称2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Blobaum A L Byers F W Bridges T M et al. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo.[J]. Drug Metabolism & Disposition the Biological Fate of Chemicals 2015 43(11):1718.
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