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Dermorphin
CAS No. 77614-16-5
Dermorphin ( —— )
产品货号. M20802 CAS No. 77614-16-5
Dermorphin 是 μ-阿片受体 (MOR) 激动剂的激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1482 | 有现货 |
|
生物学信息
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产品名称Dermorphin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Dermorphin 是 μ-阿片受体 (MOR) 激动剂的激动剂。
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产品描述Dermorphin is agonist of μ-opioid receptor (MOR) agonist.
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体外实验Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor.
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体内实验——
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同义词——
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通路Endocrinology/Hormones
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靶点Opioid Receptor
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受体μ-opioid receptor
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研究领域——
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适应症——
化学信息
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CAS Number77614-16-5
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分子量802.87
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分子式C40H50N8O10
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 120 mg/mL (149.46 mM)
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SMILESCC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(Cc1ccccc1)C(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(CO)C(N)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Robinson M A Guan F Mcdonnell S et al. Pharmacokinetics and pharmacodynamics of dermorphin in the horse[J]. Journal of Veterinary Pharmacology and Therapeutics 2015 38(4):321-329.
产品手册
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