Sultopride hydrochloride ( LIN-1418 hydrochloride )

产品货号. M20670 CAS No. 23694-17-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Sultopride hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Sultopride Hydrochloride 是一种选择性多巴胺 D2 和 D3 受体拮抗剂。
产品描述

Sultopride Hydrochloride is a selective dopamine D2 and D3 receptor antagonist.
体外实验

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体内实验

Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05).
同义词

LIN-1418 hydrochloride
通路

GPCR/G Protein
靶点

Dopamine Receptor
受体

Dopamine
研究领域

——
适应症

——

CAS Number

23694-17-9
分子量

390.93
分子式

C17H27ClN2O4S
纯度

>98% (HPLC)
溶解度

DMSO:50 mg/mL (127.90 mM)
SMILES

Cl.CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC
化学全称

N-((1-Ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride