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RP-54745
CAS No. 135330-08-4
RP-54745 ( —— )
产品货号. M20324 CAS No. 135330-08-4
RP-54745，一种潜在的抗风湿化合物。巨噬细胞刺激和白细胞介素 1 产生的抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1254 | 有现货 |
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| 10MG | ￥2014 | 有现货 |
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| 25MG | ￥3562 | 有现货 |
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| 50MG | ￥5050 | 有现货 |
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| 100MG | ￥6867 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1131 | 有现货 |
|
生物学信息
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产品名称RP-54745
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述RP-54745，一种潜在的抗风湿化合物。巨噬细胞刺激和白细胞介素 1 产生的抑制剂。
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产品描述RP-54745 a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
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体外实验RP-54745 diminishes LPS-induced interleukin-1 (IL-1) production by murine peritoneal macrophages.
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体内实验RP-54745 (5 mg/kg) is effective at moderating oral doses in different mouse models of induced arthritis and in the MRL/lpr mice, genetically predisposed to develop an autoimmune pathology including arthritic disorders. The clinical status of the MRL mice, and several of their disturbed biochemical and immunological parameters, improved after a 3-month treatment with RP-54745.
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同义词——
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通路Others
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靶点Other Targets
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受体interleukin-1
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研究领域——
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适应症——
化学信息
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CAS Number135330-08-4
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分子量297.8
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分子式C13H12ClNOS2?
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纯度>98% (HPLC)
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溶解度DMSO:62.5 mg/mL?(209.86 mM)
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SMILESCC1N(CCc2ccccc12)c1ssc(=O)c1Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Corticotropin-releas...
Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) is an immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.
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Dipropofol
Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.
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BDC2.5 mimotope 1040...
BDC2.5 mimotope 1040-51 is a mimotope peptide for diabetogenic T cell clone BDC2.5. isolated from non-obese diabetic mice.This is a effectively agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5. from non-obese diabetic (NOD) mice. T cells from prediabetic and diabetic NODs respond to BDC2.5 mimotope peptides.
