Triacanthine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

三棘嘌呤是一种植物生长物质，具有高血压和抗肿瘤活性，还具有强心、解痉和呼吸兴奋剂的作用。

Triacanthine which is a plant growth substance shows hypertensive and antitumor activity also cardiotonic antispasmodic and a respiratory analeptic.

Derivative UV spectroscopic data show that the plant growth substances 6-(γ,γ-Dimethylallylamino)purine (N6-(delta 2-isopentenyl) adenine, i6Ade)and indolylacetic acid (IAA) can bind to the yeast alcohol dehydrogenase (ADH) and affect coenzyme-enzyme binding. At fixed ethanol concentrations (27.8 and 111.1 mM) and varying NAD+ concentrations (0.033-2 mM), as well as at fixed levels of coenzyme (0.67 and 2 mM), and at varying concentrations of ethanol (1.4-111.1 mM), the rate of ethanol oxidation is significantly inhibited by i6Ade and IAA. The kinetics of the ADH reaction is affected by two inhibition constants (Ki and Ki') which correspond to the dissociation constants of complexes EI and ESI, respectively. For i6Ade the Ki=0.52±0.06 mM and Ki'=0.74±0.07 mM, and for IAA the Ki=0.88±0.03 mM and Ki'=0.99±0.02 mM.

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6-(γγ-Dimethylallylamino)purine | N6-(2-lsopentenyl)adenine

Others

Other Targets

Others

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2365-40-4

203.25

C10H13N5

>98% (HPLC)

DMSO: 40 mg/mL (196.81 mM)

C\C(C)=C\CNc1ncnc2[nH]cnc12

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(-20℃)

With Ice Pack

≥ 2 years