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Rimeporide hydrochloride
CAS No. 187870-95-7
Rimeporide hydrochloride ( EMD-87580 hydrochloride )
产品货号. M20087 CAS No. 187870-95-7
Rimeporide (EMD-87580) 是一种有效的选择性钠氢交换 1 (NHE-1) 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2090 | 有现货 |
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| 10MG | ￥3012 | 有现货 |
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| 25MG | ￥4566 | 有现货 |
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| 50MG | ￥6026 | 有现货 |
|
| 100MG | ￥8037 | 有现货 |
|
| 200MG | ￥10620 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Rimeporide hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Rimeporide (EMD-87580) 是一种有效的选择性钠氢交换 1 (NHE-1) 抑制剂。
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产品描述Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
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体外实验Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent.
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体内实验——
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同义词EMD-87580 hydrochloride
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通路Membrane Transporter/Ion Channel
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靶点Sodium Channel
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受体NHE-1
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研究领域——
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适应症——
化学信息
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CAS Number187870-95-7
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分子量369.84
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分子式C11H16ClN3O5S2
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纯度>98% (HPLC)
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溶解度DMSO: 18.5 mg/mL (50 mM)
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SMILESCl.Cc1cc(c(cc1C(=O)NC(N)=N)S(C)(=O)=O)S(C)(=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Stanbouly S et al. Sodium hydrogen exchange 1 (NHE-1) regulates connexin 43 expression in cardiomyocytes via reverse mode sodium calcium exchange and c-Jun NH2-terminal kinase-dependent pathways. J Pharmacol Exp Ther. 2008 Oct;327(1):105-13.
