L-allo-Isoleucine ( (3R)-LS-Isoleucine | L(+)-Alloisoleucine )

产品货号. M20000 CAS No. 1509-34-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

L-allo-Isoleucine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

L-别异亮氨酸是一种支链氨基酸，是L-异亮氨酸的立体异构体。它是人体血浆的常见成分（尽管含量较低）。 L-别异亮氨酸是异亮氨酸转氨作用的副产物。血浆L-别异亮氨酸源自体内L-异亮氨酸，可用于诊断枫糖浆尿病（MSUD），一种遗传性疾病。
产品描述

L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine which is derived from L-isoleucine in vivo can be used for the diagnosis of maple syrup urine disease (MSUD) a genetic disorder. Indeed plasma L-alloisoleucine levels above 5 μmol/L is the most specific and most sensitive diagnostic marker for all forms of MSUD.
体外实验

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体内实验

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同义词

(3R)-LS-Isoleucine | L(+)-Alloisoleucine
通路

Others
靶点

Other Targets
受体

Others
研究领域

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适应症

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1.Schadewaldt P et al. Significance of L-alloisoleucine in plasma for diagnosis of maple syrup urine disease. Clin Chem. 1999 Oct;45(10):1734-40.

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