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N-(5-Aminopentyl)acetamide

CAS No. 32343-73-0

N-(5-Aminopentyl)acetamide ( Monoacetylcadaverine | N-Acetyl-15-pentanediamine | N-Acetylcadaverine )

产品货号. M19992 CAS No. 32343-73-0

N-乙酰尸胺是多胺尸胺的乙酰化形式。尸胺是由活体和死亡生物体内的氨基酸分解产生的,大剂量时有毒。 N-(5-氨基戊基)乙酰胺是一种有前途的癌症和许多其他病理生理状况的生化标志物。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥113 有现货
10MG ¥151 有现货
25MG ¥230 有现货
50MG ¥352 有现货
100MG ¥521 有现货
500MG ¥1278 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥185 有现货

生物学信息

  • 产品名称
    N-(5-Aminopentyl)acetamide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    N-乙酰尸胺是多胺尸胺的乙酰化形式。尸胺是由活体和死亡生物体内的氨基酸分解产生的,大剂量时有毒。 N-(5-氨基戊基)乙酰胺是一种有前途的癌症和许多其他病理生理状况的生化标志物。
  • 产品描述
    N-Acetylcadaverine is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large doses. N-(5-Aminopentyl)acetamide is a promising biochemical marker for cancer and many other pathophysiological conditions.
  • 体外实验
    Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups which ubiquitously exists in all living organisms from bacteria to higher animals. The critical step of polyamine biosynthesis generally includes the amino acid-decarboxylating reaction to produce the primary diamines, such as cadaverine from lysine. Synthesized polyamines are implicated in a wide variety of cytoplasmic reactions such as DNA replication and protein synthesis, and are essential for proper growth and proliferation of the organisms. Cadaverine is a linear molecule that terminate at both ends with an amine functional group. These functional groups confer to the molecules multiple positive charges at physiological pH. Cadaverine is produced through the action of basic amino acid decarboxylases and is found associated with the outer membrane.
  • 体内实验
    ——
  • 同义词
    Monoacetylcadaverine | N-Acetyl-15-pentanediamine | N-Acetylcadaverine
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    32343-73-0
  • 分子量
    144.21
  • 分子式
    C7H16N2O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 25 mg/mL
  • SMILES
    CC(=O)NCCCCCN
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Paik MJ et al. Urinary polyamines and N-acetylated polyamines in four patients with Alzheimer's disease as their N-ethoxycarbonyl-N-pentafluoropropionyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode. Anal Chim Acta. 2006 Aug 18;576(1):55-60.
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