Ammonium formate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

甲酸是最简单的羧酸。甲酸是正常代谢的中间体。它通过抑制细胞色素氧化酶（电子传递链的末端电子受体）活性，导致代谢性酸中毒并破坏线粒体电子传递和能量产生。

Formic acid is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.

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Formic acid ammonium salt

Others

Other Targets

Others

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540-69-2

63.06

CH5NO2

>98% (HPLC)

DMSO:200 mM

[NH4+].[O-]C=O

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(-20℃)

With Ice Pack

≥ 2 years