Neticonazole Hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

盐酸奈替康唑是一种咪唑类抗真菌药，用于治疗皮肤真菌感染。据报道，奈替康唑是一种有效的外泌体抑制剂，可以阻断外泌体的活性。

Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.

Western Blot Analysis Cell Line:C4-2B cells Concentration:10 μM Incubation Time:48 hours Result:Decreased the levels of both Alix and Rab27a, and significantly decreased nSMase2 levels.

Animal Model:Male C57BL/6 mice (8 weeks old) given ampicillin, neomycin, metronidazole and vancomycin, and injected with SW480 cellsDosage:1 ng/kg, 10 ng/kg and 100 ng/kg Administration:Oral gavage; daily; for 15 days Result:Significantly improved the survival of IDB mice with CRC xenograft tumors.

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Microbiology/Virology

Antifungal

Antifungal

Cancer

PCa(prostatic Cancer)

130773-02-3

338.9

C17H22N2OS.HCl

>98% (HPLC)

DMSO: 50 mg/mL

Cl.CCCCCOc1ccccc1\C(=C/SC)n1ccnc1

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(-20℃)

With Ice Pack

≥ 2 years