5-DEOXYADENOSINE

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

5'-Deoxyadenosine 是正常受试者尿液中发现的氧化核苷。5'-Deoxyadenosine 具有抗正痘活性。

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material which has long been of interest in understanding the mechanism of aging neurodegenerative diseases and carcinogenesis. The normal form of deoxyadenosine used in DNA synthesis and repair is 2'-deoxyadenosine where the hydroxyl group (-OH) is at the 2' position of its ribose sugar moiety. 5'-deoxyadenosine has its hydroxyl group at the 5' position of the ribose sugar.

——

——

5′-dAdo

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

——

——

4754-39-6

251.24

C10H13N5O3

>98% (HPLC)

DMSO:10 mM;Water:20mg/mL

C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

(2R3R4S5R)-2-(6-amino-9H-purin-9-yl)-5-methyltetrahydrofuran-34-diol

(-20℃)

With Ice Pack

≥ 2 years