DL-Homocysteine ( 2-Amino-4-mercaptobutyric acid )

产品货号. M19720 CAS No. 454-29-5

DL-同型半胱氨酸是肿瘤细胞生长的潜在标志物。血浆同型半胱氨酸升高是冠心病和癌变的危险因素。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
50MG	￥100	有现货
100MG	￥128	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

DL-Homocysteine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

DL-同型半胱氨酸是肿瘤细胞生长的潜在标志物。血浆同型半胱氨酸升高是冠心病和癌变的危险因素。
产品描述

DL-Homocysteine is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.
体外实验

DL-Homocysteine (0.1-0.5 mM) significantly enhances kynurenic acid (KYNA) production in rat cortical slices, and diministes the production of at 3.0, 5.0, and 10.0 mM, with the estimated IC50 of 6.4 (5.5-7.5) mM. DL-Homocysteine dose-dependently inhibits kynurenine aminotransferases I (KATI) activity at concentrations ≥0.2 mM, with an IC50 of 0.566 (0.442-0.724) mM, and the activity of KAT II with IC50 value of 8.046 (5.804-11.154) mM.
体内实验

DL-Homocysteine (1.3 mmol/kg, i.p.) increases KYNA content (pmol/g tissue) from 8.47 ± 1.57 to 13.04 ± 2.86 and 11.4 ± 1.72 in cortex, and from 4.11 ± 1.54 to 10.02 ± 3.08 in rat hippocampus.
同义词

2-Amino-4-mercaptobutyric acid
通路

Proteasome/Ubiquitin
靶点

Endogenous Metabolite
受体

Human Endogenous Metabolite
研究领域

——
适应症

——

化学信息

CAS Number

454-29-5
分子量

135.19
分子式

C4H9NO2S
纯度

>98% (HPLC)
溶解度

DMSO:10 mM;Water:Soluble
SMILES

NC(CCS)C(O)=O
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.DL-Homocysteine et al. Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist kynurenic acid. J Neurosci Res. 2005 Feb 1;79(3):375-82.

计算器

浓度计算器

摩尔计算器

分子量计算器

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