Aniline ( Phenylamine | Aminobenzen )

产品货号. M19715 CAS No. 62-53-3

苯胺通过铁超载和血红素加氧酶 1 上调诱导氧化应激而对脾脏有毒。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
100MG	获取报价	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

Aniline
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

苯胺通过铁超载和血红素加氧酶 1 上调诱导氧化应激而对脾脏有毒。
产品描述

Aniline has been reported to be toxic to the spleen via iron overload and induction of oxidative stress via Heme Oxygenase 1 up-regulation. Toxicity of this agent on the spleen is characterized by hyperplasia fibrosis and vascular congestion in rats. Studies suggest that this compound causes significant increase in both p-IKKα and p-IKKβ which in-turn increases NF-κB and AP-1 binding activity. In other experiments Aniline displays a capacity to induce methemoglobinemia glutathione depletion membrane cytoskeletal changes loss of circulating blood cells and adversely affects blood stability.
体外实验

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体内实验

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同义词

Phenylamine | Aminobenzen
通路

Proteasome/Ubiquitin
靶点

Endogenous Metabolite
受体

Human Endogenous Metabolite
研究领域

——
适应症

——

化学信息

CAS Number

62-53-3
分子量

93.13
分子式

C6H7N
纯度

>98% (HPLC)
溶解度

DMSO:10 mM
SMILES

Nc1ccccc1
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Bomhard E M Herbold B A . Genotoxic Activities of Aniline and its Metabolites and Their Relationship to the Carcinogenicity of Aniline in the Spleen of Rats[J]. Critical Reviews in Toxicology 2005 35(10):783-835.

计算器

浓度计算器

摩尔计算器

分子量计算器

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