DL-Glyceraldehyde

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

甘油醛是由甘油醛脱氢酶的作用产生的，该酶使用 NADP 作为辅因子将甘油转化为甘油醛。当甘油醛含量足够高时，它可以是一种细胞毒素和诱变剂。细胞毒素是一种杀死细胞的化合物。

Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. Glyceraldehyde-modified proteins appear to be cytotoxic depress intracellular glutathione levels and induce reactive oxygen species (ROS) production (PMID: 14981296 ). Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.

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Glyceric aldehyde

Endocrinology/Hormones

Reductase

Aldose reductase

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56-82-6

90.08

C3H6O3

>98% (HPLC)

DMSO:10 mM

OCC(O)C=O

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(-20℃)

With Ice Pack

≥ 2 years