Creatine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

肌酸是一种存在于脊椎动物组织和尿液中的氨基酸。在肌肉组织中，肌酸通常以磷酸肌酸的形式存在。

Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. Creatine functions as part of the cell's energy shuttle. The high energy phosphate group of ATP is transferred to creatine to form phosphocreatine in the following reaction: Cr + ATP <-> PCr + ADP. This reaction is reversibly catalyzed by creatine kinase. In the human body creatine is synthesized mainly in the liver by the use of parts from three different amino acids: arginine glycine and methionine. 95% of it is later stored in the skeletal muscles and the rest is stored in the brain heart and testes.

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Methylguanidoacetic acid

Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

Neurological Disease

Amyotrophic lateral sclerosis; Huntington's disease; Metabolic disorders; Neuromuscular disorders; Parkinson's disease

57-00-1

131.13

C4H9N3O2

>98% (HPLC)

DMSO:10uM;Water:24 mg/mL(183 mM)

CN(CC(O)=O)C(N)=N

Glycine N-(aminoiminomethyl)-N-methyl-

(-20℃)

With Ice Pack

≥ 2 years