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O-Phosphorylethanolamine
CAS No. 1071-23-4
O-Phosphorylethanolamine ( —— )
产品货号. M19543 CAS No. 1071-23-4
磷酸乙醇胺 (PE) 是磷脂代谢的磷酸单酯代谢物。 PE是磷脂合成的前体，也是磷脂分解的产物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥218 | 有现货 |
|
| 500MG | ￥284 | 有现货 |
|
| 1G | ￥321 | 有现货 |
|
生物学信息
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产品名称O-Phosphorylethanolamine
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述磷酸乙醇胺 (PE) 是磷脂代谢的磷酸单酯代谢物。 PE是磷脂合成的前体，也是磷脂分解的产物。
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产品描述Phosphoethanolamine (PE) is a phosphomonoester metabolite of the phospholipid metabolism. PE is a precursor of phospholipid synthesis and a product of phospholipid breakdown. Phosphomonoesters are present at much higher levels in the brain than in other organs. In developing the brain phosphomonoesters are normally elevated during the period of neuritic proliferation. This also coincides with the occurrence of normal programmed cell death and synaptic pruning in developing the brain. These findings are consistent with the role of phosphomonoesters in membrane biosynthesis. PE shows a strong structural similarity to the inhibitory neurotransmitter GABA and the GABAB receptor partial agonist 3-amino-propylphosphonic acid. PE is a phosphomonoester which is decreased in post-mortem Alzheimer's disease (AD) brain.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number1071-23-4
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分子量141.06
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分子式C2H8NO4P
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纯度>98% (HPLC)
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溶解度H2O:250 mg/mL (1772.30 mM; Need ultrasonic)
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SMILESNCCOP(O)(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Tetramethylammonium
Tetramethylammonium ion has limited toxicity of dermal exposure, but fatal effects can be introduced by pre-treatment with hydroxide ion.
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3-Methoxydaidzin
3'-Methoxydaidzin has antioxidation activity, it may be a potential neuroprotective substance in Gegen Qinlian decoction.
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CALP1
Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM). Shown to protect pancreatic acinar cells from gossypol induced necrosis. Inhibits VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo.
