Tenuifoliside A

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Tenuifoliside A 具有抗细胞凋亡、神经保护活性。 tenuifoliside A 具有抗炎作用，该作用是通过抑制 NF-κB 和 MAPK 通路介导的。

Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.

Tenuifoliside A (6-30 μM; 24 hours) increases the C6 cells viabilitysignificantly by concentration dependent manner. But the viability of the 60 μM treatment group is suppressed. Only 60 μM TFSA induced the release of LDH, shows a toxic effect.Tenuifoliside A (10 μM; 2, 5, 7, 10, 15, 30, 45 and 60 mins) elicits a rapid (starting at 2 min) and marked induction of ERK1/2 phosphorylation peaking at 5 min. And,the enhanced levels of phospho-ERK induced by TFSA are partially blocked by ERK inhibitor U0126.

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Others

Other Targets

Others

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139726-35-5

682.6

C31H38O17

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (146.49 mM)

COc1cc(cc(OC)c1OC)/C=C/C(=O)OC[C@H]4O[C@H](O[C@@]3(CO)O[C@@H](CO)[C@H](O)[C@H]3OC(=O)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]4O

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(-20℃)

With Ice Pack

≥ 2 years