Corylin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Corylin 是从补骨脂 (Psoralea corylifolia L) 中分离出来的主要生物活性化合物；它具有抗生素或抗癌活性。

Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.

Western Blot Analysis Cell Line:HepG2 and Huh7 cells Concentration:3-30 μM Incubation Time:24-48 h Result:Reduced the expression of EMT-promoting proteins such as N-cadherin, vimentin, slug, and twist.

Animal Model:HFD- and DIO-treated miceDosage:50-100 mg/kg Administration:Oral gavage (p.o.), daily, 9 weeks Result:Reduced the weight of subcutaneous, visceral WAT, and body.Decreased the size of WAT adipocyte. Increased insulin sensitivity, mitochondrial biogenesis, and β-oxidation.Reduced serum levels of insulin and leptin and improved HOMA-IR.

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Metabolic Enzyme/Protease

MMP

Others

Cancer

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53947-92-5

320.3

C20H16O4

>98% (HPLC)

DMSO : ≥ 100 mg/mL 312.17 mM; H2O : < 0.1 mg/mL

CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C

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(-20℃)

With Ice Pack

≥ 2 years