Methyl gallate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

没食子酸甲酯是一种逆转录酶抑制剂，具有抗氧化、抗 HIV-1 和 HIV-1 酶抑制活性。

Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.

The growth of A. viscosus is inhibited completely by a low dose of Methyl gallate (MIC=1 mg/mL). S. mutans and . sobrinus show intermediate sensitivity to Methyl gallate (MIC=2-4 mg/mL), whereas the growth of Lactobacillus spp. is inhibited completely at a relatively high concentration (MIC=8 mg/mL). Methyl gallate, in a concentration of 100 mM, could alleviate lipid peroxidation of the cells exposed to a short-term H2O2 treatment. In addition, Methyl gallate-treated cells could prevent intracellular glutathione (GSH) from being depleted following an exposure of H2O2 (8.0 mM) for a 3 h period. Methyl gallate inhibits Treg cell-suppressive effects on effector CD4+ T cells and Treg migration toward tumor environment. Furthermore, forkhead box P3 (Foxp3) expression is also significantly decreased by methyl gallate.

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Gallincin | NSC 363001

Others

Other Targets

Reverse Transcriptase

Others-Field

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99-24-1

184.14

C8H8O5

>98% (HPLC)

DMSO : ≥ 160 mg/mL; 868.86 mM

COC(=O)c1cc(c(c(c1)O)O)O

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(-20℃)

With Ice Pack

≥ 2 years