Poliumoside ( —— )

产品货号. M19272 CAS No. 94079-81-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Poliumoside
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Poiumoside 是一种天然化合物，可显着抑制晚期糖基化终产物的形成，IC50 值为 4.6-25.7 μM。
产品描述

Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase with IC50 values of 0.85 μM.Poliumoside has oxidant scavenging, antibacterial and hemostasis capacities, it can inhibit Biofilm-forming Staphylococcus aureus in mice.
体外实验

Poliumoside inhibits AGE formation and RLAR, with IC50s of 19.69, and 8.47 μM, respectively.Poliumoside (5-30 μM; 3 h) inhibits AAPH-induced hemolysis of rat red blood cells in vitro.Poliumoside (12.5-100 μM; pretreated 2 h) inhibits the release of TNF-α and IL-6 in LPS-induced RAW 264.7?cells.
体内实验

Poliumoside inhibits vessel dilation in larval zebrafish.
同义词

——
通路

Microbiology/Virology
靶点

Antifungal
受体

Aldose reductase
研究领域

Metabolic Disease
适应症

——

CAS Number

94079-81-9
分子量

770.73
分子式

C35H46O19
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 100 mg/mL (129.75 mM)
SMILES

Oc1ccc(cc1O)/C=C/C(=O)O[C@@H]5[C@@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@H]5O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O
化学全称

——

1.Tai BH, et al.Total peroxynitrite scavenging capacity of phenylethanoid and flavonoid glycosides from the flowers of Buddleja officinalis.

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