Detomidine HCl

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Detomidine HCl 通过激活 α2 儿茶酚胺受体介导产生剂量依赖性镇静和镇痛作用。

Detomidine HCl is an alpha2-Adrenoreceptor agonist with sedative properties.(In Vitro):Currently, detomidine is only licenced for use in horses. α2-adrenergic agonists produce dose-dependent analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.

Currently, detomidine is only licenced for use in horses. α2-adrenergic agonists produce dose-dependent analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.

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Detomidine hydrochloride | Detomidine HCl | MPV253

Cell Cycle/DNA Damage

HDAC

α2 catecholamine receptors

Neurological Disease

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90038-01-0

222.71

C12H14N2·HCl

>98% (HPLC)

DMSO : ≥ 100 mg/mL 449.01 mM H2O : 20 mg/mL 89.80 mM

Cl.CC1=C(C)C(CC2=CNC=N2)=CC=C1

5-[(2,3-Dimethylphenyl)methyl]-1H-imidazole hydrochloride

(-20℃)

With Ice Pack

≥ 2 years