Quinolinic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Quinolinic Acid 是一种内源性 N-甲基-D-天冬氨酸 (NMDA) 受体激动剂，由 L-色氨酸通过犬尿氨酸途径合成。

Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.

Quinolinic acid (0-50 mM; 24 hours) decreases the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM in N18D3 cells. Cell Viability Assay Cell Line:N18D3 cells, hybrid neuronal cell line obtained by fusion of dorsal root ganglions isolated from 4-week-old Balb/C mouse with the mouse neuroblastoma N18TG2 cells Concentration:0, 10, 20, 30, 40, 50 mM Incubation Time:24 hoursResult:There was a corresponding decrease in the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM.

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Others

Other Targets

NMDA receptor

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89-00-9

173.17

C10H7NO2

>98% (HPLC)

DMSO : 33.33 mg/mL 199.44 mM

OC(=O)c1cccnc1C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years