Rilmenidine Phosphate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Rilmenidine Phosphate 是一种选择性 I(1) 咪唑啉受体激动剂，用于治疗高血压。

Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.(In Vitro):Rilmenidine provides antihypertensive efficacy comparable with that of diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors.Rilmenidine phosphate (25-100 μM; 24 hours) inhibits K562 cell proliferation.(In Vivo):Rilmenidine phosphate-treated N171-82Q mice (i.p.; 4-times a week) displays significant improved forelimb grip strength and all limbs grip strength from 12 to 22 weeks of age.Rilmenidine phosphate decreases levels of mutant huntingtin.

Rilmenidine provides antihypertensive efficacy comparable with that of diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors.Rilmenidine phosphate (25-100 μM; 24 hours) inhibits K562 cell proliferation. Cell Proliferation Assay Cell Line:K562 cells Concentration:25, 50, 100 μM Incubation Time:24 hours Result:Dose-dependently inhibited K562 colony formation.

Rilmenidine phosphate-treated N171-82Q mice (i.p.; 4-times a week) displays significant improved forelimb grip strength and all limbs grip strength from 12 to 22 weeks of age.Rilmenidine phosphate decreases levels of mutant huntingtin.

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Others

Other Targets

I(1) imidazoline receptor

Others-Field

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85409-38-7

278.24

C10H19N2O5P

>98% (HPLC)

In Vitro:?H2O : 83.33 mg/mL (299.49 mM)

C1CC1C(C1CC1)NC1=NCCO1.OP(=O)(O)O

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(-20℃)

With Ice Pack

≥ 2 years