Linderalactone ( Linderalactone )

产品货号. M19045 CAS No. 728-61-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Linderalactone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

乌药内酯对人中性粒细胞响应 fMLP/CB 产生超氧阴离子显示出显着的抑制作用，IC5 值为 8.48 μg/mL。
产品描述

Linderalactone is an NSAID isolated from Lindera aggregata.
体外实验

Cell Viability Assay Cell Line:Lung cancer A549 cells Concentration:0 μM, 1.6 μM, 3.2 μM, 6.25 μM, 12.5 μM, 25 μM, 50 μM, 100 μM Incubation Time:24 hours Result:Inhibited the growth of A549 cells concentration-dependently.Apoptosis Analysis Cell Line:Lung cancer A549 cells Concentration:7.5 μM, 15 μM, 30 μM Incubation Time:Result:Induced apoptosis in A549 cells in a dose-dependent manner. Cell Cycle Analysis Cell Line:Lung cancer A549 cells Concentration:7.5 μM, 15 μM, 30 μM Incubation Time:24 hours Result:Induced G2/M cell cycle arrest.Western Blot Analysis Cell Line:Lung cancer A549 cells Concentration:7.5 μM, 15 μM, 30 μM Incubation Time:Result:Inhibited the JAK/STAT pathway in A549 cells.
体内实验

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同义词

Linderalactone
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

728-61-0
分子量

244.29
分子式

C15H16O3
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 33.33 mg/mL (136.44 mM)
SMILES

CC1=CCCC2=CC(C3=C(C1)OC=C3C)OC2=O
化学全称

(R,7Z,10E)-3,11-dimethyl-4,8,9,12-tetrahydro-6H-4,7-(metheno)furo[3,2-c][1]oxacycloundecin-6-one

计算器

产品手册

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