Kaurenoic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

贝壳杉烯酸在醋酸诱导的结肠炎中具有抗炎作用，可降低 MDA 水平。

Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part, by the opening of ATP-sensitive potassium channels. Kaurenoic acid exhibits an analgesic effect in a consistent manner and that its mechanisms involve the inhibition of cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. Kaurenoic acid derivatives have an antimicrobial activity of substituted on carbon-15 at concentrations greater than or equal to 250 μg/ml. Kaurenoic acid has inhibitory effects on the LPS-induced inflammatory response in RAW264.7 macrophages.

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CCRIS 1514 | Kauren-19-oic acid

Others

Other Targets

Others

Inflammation/Immunology

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6730-83-2

302.45

C20H30O2

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (330.63 mM)

C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@H](C3)C(=C)C4)(C)C(=O)O

(4R,4aS,6aS,9S,11aR,11bS)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid

(-20℃)

With Ice Pack

≥ 2 years