Mitoxantrone ( mitozantrone )

产品货号. M18958 CAS No. 65271-80-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Mitoxantrone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

米托蒽醌是一种具有抗肿瘤活性的蒽二酮抗生素。米托蒽醌插入并交联 DNA，从而破坏 DNA 和 RNA 复制。
产品描述

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
体外实验

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体内实验

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同义词

mitozantrone
通路

Others
靶点

Other Targets
受体

Topo II
研究领域

Cancer
适应症

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1. Bellosillo B, et al. Br J Haematol, 1998, 100(1), 142-146.

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