Cefoperazone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

头孢哌酮与细菌细胞壁内膜上的青霉素结合蛋白 (PBP) 结合并使其失活。

Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. It can inhibit rMrp2-mediated [3H]E217βG uptake (IC50: 199 μM).

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Cefobid | Cefozon | T1551 | T 1551

Others

Other Targets

Antibacterial

Infection

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62893-19-0

645.67

C25H27N9O8S2

>98% (HPLC)

DMSO : ≥ 100 mg/mL 154.88 mM H2O : < 0.1 mg/mL

[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=O

(6R,7R)-7-((R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(-20℃)

With Ice Pack

≥ 2 years