Synephrine HCl

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

SynephrineHCl (Oxedrine, p-Synephrine) 是一种作用于拟交感神经 α-肾上腺素能受体 (AR) 的激动剂。

SynephrineHCl (Oxedrine, p-Synephrine) is an agonist that acts on sympathomimetic α-adrenergic receptor (AR).(In Vivo):Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine.

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Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine. Animal Model:Portal vein ligation (PVL) or bile duct ligation (BDL) rats Dosage:1 mg/kg per 12 hours Administration:Oral gavage; for 8 days Result:The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.

Oxedrine hydrochloride

Others

Other Targets

α-adrenergic receptor

Neurological Disease

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5985-28-4

203.67

C9H13NO2·HCl

>98% (HPLC)

DMSO : ≥ 52 mg/mL; 255.31 mM

C(c1ccc(cc1)O)(CNC)O.Cl

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(-20℃)

With Ice Pack

≥ 2 years