Atractylodin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

苍术具有较高的脂肪酶抑制活性（IC5：39.12 μM）； Atractylodin 对赤霉成虫具有很强的驱避活性（LD50：1.83 μg/cm）。

Atractylodin has high lipase inhibitory activity (IC5:39.12?μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83?μg/cm). The repellency of Atractylodin (0.63?μg/cm) can achieve >90%.

Cell Viability Assay Cell Line:NCM460, SW480, HCT116 Concentration:1, 10, 25, 50, 100 μM Incubation Time:24 h Result:Decreased viability at a concentration of 100 μM in HCT116 cells.Western Blot Analysis Cell Line:HCT116 Concentration:50 μM Incubation Time:1 h Result:Inhibited TNF-α-induced phosphorylation of NF-κB p65.

Animal Model:DSS-Induced Colitis Mouse Model Dosage:40 mg/kg Administration:i.p.Result:Reduced colitis symptoms and increased survival rate.Animal Model:NAFLD mice model Dosage:20, 40, 80 mg/kg Administration:i.g.Result:Reduced the release of ALT, AST, ROS and MDA.

Atractydin

Apoptosis

NF-κB

lipase

Others-Field

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55290-63-6

182.22

C13H10O

>98% (HPLC)

DMSO : ≥ 6 mg/mL 32.93 mM; H2O : < 0.1 mg/mL

C/C=C/C#CC#C/C=C/c1ccco1

——

(-20℃)

With Ice Pack

≥ 2 years