n-Butylidenephthalide ( Butylidenephthalide | BP | 3-Butylidene Phthalide )

产品货号. M18790 CAS No. 551-08-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

n-Butylidenephthalide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

(Z)-3-丁基亚苯酞具有降血糖作用，是由于在肠道水平抑制 α-葡萄糖苷酶，以非竞争性方式抑制酵母-α-葡萄糖苷酶的活性 (IC(5) 2.35 mM)，K(i) 4.86毫米。
产品描述

Butylidenephthalide is an inhibitor of platelet-derived growth factor (PDGF). Butylidenephthalide activity leads to the reduction of liver fibrosis, increased Nur77 (NR4A1) expression, and downregulation of EMT-related genes such as Snail (Snail/SNAI1) and Slug (Slug/SNAI2).
体外实验

3-Butylidenephthalide (Butylidenephthalide) abrogates the myofibroblasts activation and mesenchymal transdifferentiation in oral submucous fibrosis.
体内实验

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同义词

Butylidenephthalide | BP | 3-Butylidene Phthalide
通路

Membrane Transporter/Ion Channel
靶点

TRP/TRPV Channel
受体

α-glucosidase
研究领域

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适应症

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