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Herniarin
CAS No. 531-59-9
Herniarin ( 7-Methoxycoumarin | Methyl umbelliferyl ether )
产品货号. M18747 CAS No. 531-59-9
Herniarin 是一种天然香豆素，具有抗肿瘤作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥143 | 有现货 |
|
生物学信息
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产品名称Herniarin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Herniarin 是一种天然香豆素，具有抗肿瘤作用。
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产品描述Herniarin is a natural coumarin with antitumor effect.(In Vitro):Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
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体外实验Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
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体内实验——
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同义词7-Methoxycoumarin | Methyl umbelliferyl ether
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通路Others
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靶点Other Targets
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number531-59-9
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分子量176.17
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分子式C10H8O3
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 125 mg/mL; 709.54 mM
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SMILESCOc1ccc2ccc(=O)oc2c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.
产品手册
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