Herniarin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Herniarin 是一种天然香豆素，具有抗肿瘤作用。

Herniarin is a natural coumarin with antitumor effect.(In Vitro):Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.

Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.

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7-Methoxycoumarin | Methyl umbelliferyl ether

Others

Other Targets

Others

Others-Field

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531-59-9

176.17

C10H8O3

>98% (HPLC)

DMSO : ≥ 125 mg/mL; 709.54 mM

COc1ccc2ccc(=O)oc2c1

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(-20℃)

With Ice Pack

≥ 2 years