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Bergaptol
CAS No. 486-60-2
Bergaptol ( 5-Hydroxypsoralen | 4-Hydroxybergapten )
产品货号. M18628 CAS No. 486-60-2
Bergaptol 是 CYP3A4 酶脱苄基活性的有效抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥189 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Bergaptol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Bergaptol 是 CYP3A4 酶脱苄基活性的有效抑制剂。
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产品描述Bergaptol shows very good radical scavenging activity. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.
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体外实验Western Blot Analysis Cell Line:LPS-induced RAW264.7 cells Concentration:50 μg/mL Incubation Time:24 h Result:Inhibited JNK phosphorylation and NF-κB activation.Inhibited NF-κB P65 translocation from the cytosol to nucleus.
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体内实验Animal Model:LPS (40 μg/kg, i.c.v.)-treated miceDosage:10-40 mg/kg Administration:i.p., once a day for two week Result:Reduced LPS-induced fixation and cleavage of neuronal nuclei in the CA1 region of the hippocampus (H&E staining).Increasead the dendritic spine density of mice.Inhibited LPS-induced neuroinflammation.
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同义词5-Hydroxypsoralen | 4-Hydroxybergapten
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通路Others
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靶点Other Targets
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受体Others
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研究领域Cancer
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适应症——
化学信息
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CAS Number486-60-2
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分子量202.16
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分子式C11H6O4
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 50 mg/mL 247.33 mM; H2O : < 0.1 mg/mL
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SMILESC1=CC(=O)OC2=CC3=C(C=CO3)C(=C21)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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