Isofraxidin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Isofraxidin 通过 ROS/线粒体途径以不依赖于 p53 的方式保护白血病细胞免受辐射诱导的细胞凋亡。

Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.

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Isofraxidin | Phytodolor

Others

Other Targets

p38|ERK

Others-Field

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486-21-5

222.19

C11H10O5

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (1125.16 mM)

COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O

7-Hydroxy-6,8-dimethoxychromen-2-one

(-20℃)

With Ice Pack

≥ 2 years