Zigu-glucoside I

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

紫玉糖苷I具有抗炎活性，可作为化妆品活性成分。

Ziyuglycoside I has anti-inflammatory activity, could be used as an active ingredient for cosmetics.

Ziyuglycoside I (5-160 μM; 24 hours) reveals a marked anti-proliferation activity with an IC50 value of 13.96 μM in MDA-MB-231 cells.Ziyuglycoside I (5-20 μM; 24 hours) induces MDA-MB-231 cell apoptosis by increasing the percentage of apoptotic cells from 2.43% to 44.76% at 20 μM.Ziyuglycoside I (5-20 μM; 24 hours) induces the cleavage of caspas-8, caspase-9, and caspase-3, up-regulates the pro-apoptotic protein Bax, and down-regulates anti-apoptotic protein Bal-2, dose-dependently reduces the level of mito-cyto c expression. Cell Viability Assay Cell Line:MDA-MB-231 cells Concentration:5 μM, 10 μM, 20 μM, 40 μM, 80 μM, and 160 μM Incubation Time:24 hours Result:Showed cytotoxicity on MDA-MB-231 cells.Cell Cycle Analysis Cell Line:MDA-MB-231 cells Concentration:5 μM, 10 μM, and 20 μM Incubation Time:24 hours Result:Induced G2/M phase arrest and apoptosis on MDA-MB-231 CellsWestern Blot Analysis Cell Line:MDA-MB-231 cells Concentration:5 μM, 10 μM, and 20 μM Incubation Time:24 hours Result:Induced apoptosis in MDA-MB-231 Cells through Intrinsic and Extrinsic Pathways.

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Others

Other Targets

Others

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35286-58-9

766.97

C41H66O13

>98% (HPLC)

In Vitro:?Methanol : 125 mg/mL (162.98 )

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(-20℃)

With Ice Pack

≥ 2 years