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PJ34
CAS No. 344458-19-1
PJ34 ( —— )
产品货号. M18454 CAS No. 344458-19-1
PJ34 HCl 是 PJ34 的盐酸盐，PJ34 是一种 PARP 抑制剂，EC50 为 20 nM，与 PARP1/2 具有同等效力。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥441 | 有现货 |
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| 25MG | ￥813 | 有现货 |
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| 50MG | ￥1311 | 有现货 |
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| 100MG | ￥2264 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PJ34
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PJ34 HCl 是 PJ34 的盐酸盐，PJ34 是一种 PARP 抑制剂，EC50 为 20 nM，与 PARP1/2 具有同等效力。
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产品描述PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体PARP1| PARP2
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研究领域Cancer
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适应症——
化学信息
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CAS Number344458-19-1
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分子量295.34
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分子式C17H17N3O2
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纯度>98% (HPLC)
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溶解度DMSO : 30 mg/mL 101.58 mM
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SMILESCN(C)CC(=O)Nc1cc2c([nH]c(=O)c3ccccc23)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Bullatine B
Bullatine B 具有镇痛/抗炎特性。
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ASC-JM-17
ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicity of the mutant androgen receptor (AR) responsible for SBMA in cell, fly and mouse models. Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap ‘n’ collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies.
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Prosaptide TX14(A)
Potent GPR37L1 and GPR37 agonist (EC50 values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs cell survival in both Schwann cells and oligodendrocytes; neuroprotective and glioprotective.
