Chelerythrine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Chelerythrine 是一种众所周知的蛋白激酶 C 抑制剂。

Chelerythrine may have antimanic effect . Chelerythrine can inhibit telomerase activity. Chelerythrine is a well-known protein kinase C inhibitor.Chelerythrine has potential antiproliferative and antitumor effects.

Western Blot Analysis Cell Line:A549 and NCI-H1299 cells Concentration:10, 15, 20 μM Incubation Time:24 h Result:Induced expression of LC3-II in a beclin 1-dependent way.

Animal Model:Unilateral ureteral obstruction (UUO) induced neonatal ratsDosage:5 mg/kg Administration:i.p., daily Result:Attenuated kidney injury (Increased kidney weight and restored renal function).Inhibited UUO-induced upregulated kidney injury molecule-1 expression, apoptosis, and renal fibrosis.

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Angiogenesis

PDE

Others

Cancer

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34316-15-9

348.37

C21H18NO4+

>98% (HPLC)

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C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5

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(-20℃)

With Ice Pack

≥ 2 years