Dehydrocorydalin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

DeHydrocorydaline 通过抑制 NSCLC 细胞中的 MMP 和 Bcl-2 信号传导发挥抗转移潜力。

Dehydrocorydaline exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSCLC cells. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914?ug/mL). Dehydrocorydaline has anti-inflammatory and antinociceptive effects. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.

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13-Methylpalmatine

Others

Other Targets

Others

Cancer

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30045-16-0

366.43

C22H24NO4+

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (68.23 mM)

CC1=C2C=CC(=C(C2=C[N+]3=C1C4=CC(=C(C=C4CC3)OC)OC)OC)OC

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(-20℃)

With Ice Pack

≥ 2 years