Dimethylacrylshikonin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

二甲基丙烯紫草素是一种有前途的化合物，可用于开发改进的肿瘤放射治疗策略。

Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significantly suppressed tumor growth of the HCT-116 xenograft. (b) Dimethylacrylshikonin significantly suppressed the growth of H(22) transplantable hepatoma, and induced the activation of caspase-3 . (c) Dimethylacrylshikonin inhibited growth of gastric cancer SGC-791 cells by inducing ERK signaling pathway. Dimethylacrylshikonin inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-κB pathway.

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Others

Antioxidant

ERK

Others-Field

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24502-79-2

370.4

C21H22O6

>98% (HPLC)

In Vitro:?DMSO : 12.5 mg/mL (33.75 mM)

CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)C=C(C)C)C

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(-20℃)

With Ice Pack

≥ 2 years