Saikosaponin C ( Saikosaponin C )

产品货号. M18225 CAS No. 20736-08-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Saikosaponin C
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Saikosaponin C 通过抑制 caspase-3 激活和 caspase-3 介导的 FAK 降解，有效抑制 LPS 诱导的细胞凋亡。
产品描述

Saikosaponin C is one of the major active constituents of dried Radix bupleuri root that has been widely used in China to treat a variety of conditions. Recently, saikosaponins have been reported to have properties of cell growth inhibition, inducing cancer cells differentiation and apoptosis.
体外实验

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体内实验

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同义词

Saikosaponin C
通路

Others
靶点

Other Targets
受体

Caspase-3
研究领域

Others-Field
适应症

——

CAS Number

20736-08-7
分子量

927.14
分子式

C48H72O17
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 100 mg/mL (107.86 mM)
SMILES

[C@@H]1([C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)O[C@H]1CC[C@]2([C@H](C1(C)C)CC[C@]1([C@@]3(C[C@@H]([C@@]45CCC(C[C@H]4[C@]3(C=C[C@H]21)OC5)(C)C)O)C)C)C)CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
化学全称

(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-((6aR,6bS,8R,12aS,14bS)-8-hydroxy-4,4,6a,6b,11,11,14b-heptamethyl-2,3,4,4a,5,6,6a,6b,7,8,10,11,12,12a,14a,14b-hexadecahydro-1H,9H-12b,8a-(epoxymethano)picen-3-yl)-6-(hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol

1.Lee TH1, Chang J2, Kim BM3. 2014 Mar 14;445(3):615-21.

计算器

产品手册

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