Gracillin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Gracillin 可诱导 HL60 细胞的细胞周期停滞、氧化应激和细胞凋亡，具有开发为抗肿瘤药物的潜力。

Gracillin is a steroidal saponin that has been found in C. speciosus and has diverse biological activities. Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1.

Apoptosis Analysis Cell Line:A549 cells Concentration:0-4 μM Incubation Time:24 h Result:Induced morphological changes.Apoptosis rate: 6.56%-67.43%.

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Gracillin | NSC-698787 | NSC 698787 | NSC698787

Others

Other Targets

cell cycle arrest

Cancer

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19083-00-2

885.05

C45H72O17

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (112.99 mM)

[C@@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)O[C@@H]1CC2=CC[C@H]3[C@@H]4C[C@@H]5O[C@@]6([C@H]([C@@H]5[C@]4(CC[C@@H]3[C@]2(CC1)C)C)C)CC[C@H](CO6)C)CO)O

(2S,3R,4S,5R,6R)-2-(((2R,3R,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-(((4S,5'R,6aR,6bS,8aR,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)-5-(((2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

(-20℃)

With Ice Pack

≥ 2 years