Ginsenoside Rg5 ( —— )

产品货号. M18157 CAS No. 186763-78-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ginsenoside Rg5
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

人参皂苷 Rg5 可能是治疗阿尔茨海默病的有益化合物。
产品描述

Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

IGF-1R
研究领域

Neurological Disease
适应症

——

CAS Number

186763-78-0
分子量

767.01
分子式

C42H70O12
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 50 mg/mL (65.19 mM)
SMILES

CC(=CCC=C(C)C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)C)O)C)C
化学全称

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计算器

产品手册

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