Madecassic acid ( —— )

产品货号. M18146 CAS No. 18449-41-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Madecassic acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

羟基积雪草酸是从积雪草的全草中提取的。
产品描述

Madecassic acid is extracted from the whole herb of Centella asiatica.
体外实验

Western Blot Analysis Cell Line:RAW 264.7 murine macrophage cell Concentration:50, 100, 150 μM Incubation Time:24 h followed by LPS (1 μg/mL) treatment for 4 h Result:Inhibited LPS-induced iNOS and COX-2 protein expression i in a dose -dependent manner.
体内实验

Animal Model:Colitis mice induced by2.5% DSS Dosage:25?mg/kg/day Administration:Oral gavage (p.o.) , 10 days Result:Decreased the number of γδT17 cells in the colons.Reduced the expression of IL-17 in colon tissues.
同义词

——
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

18449-41-7
分子量

504.71
分子式

C30H48O6
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 62.5 mg/mL (123.84 mM)
SMILES

C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(C[C@H]([C@@H]3[C@@]4(C[C@H]([C@@H]([C@@]3(C)CO)O)O)C)O)C)[C@@H]2[C@H]1C)C)C(=O)O
化学全称

——

1. Zhang H, et al. J BUON. 2014 Apr-Jun;19(2):372-6.

计算器

产品手册

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