UNC669 ( —— )

产品货号. M17941 CAS No. 1314241-44-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

UNC669
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

UNC669 是一种有效且特异性的 MBT（恶性脑肿瘤）抑制剂，对 L3MBTL1/3 的 IC50 为 4.2/3.1 uM。
产品描述

UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
体外实验

L3MBTL1, a paralogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a methylation state-dependent manner and contributes to higher order chromatin structure and transcriptional repression. Similar to L3MBTL1, the closely related protein, L3MBTL3, also contains three MBT repeats and has been shown to play a role in meduloblastoma formation and normal hematopoiesis in humans.
体内实验

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同义词

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通路

Autophagy
靶点

Autophagy
受体

L3MBTL1| L3MBTL3| L3MBTL4
研究领域

Others-Field
适应症

——

1. Herold JM, et al. J Med Chem. 2011, 54(7), 2504-2511.

计算器

产品手册

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