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MHP
CAS No. 1104874-94-3
MHP ( Defensamide | methyl caprooyl tyrosinate | MHP )
产品货号. M17816 CAS No. 1104874-94-3
MHP 是鞘氨醇激酶 (SPHK1) 的激活剂，可显着刺激 KC 中 CAMP mRNA 和蛋白质的产生。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥516 | 有现货 |
|
| 5MG | ￥945 | 有现货 |
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| 10MG | ￥1834 | 有现货 |
|
| 25MG | ￥3134 | 有现货 |
|
| 50MG | ￥4455 | 有现货 |
|
| 100MG | ￥6021 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1093 | 有现货 |
|
生物学信息
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产品名称MHP
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述MHP 是鞘氨醇激酶 (SPHK1) 的激活剂，可显着刺激 KC 中 CAMP mRNA 和蛋白质的产生。
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产品描述Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.
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体外实验MHP (50-250 μM for 24 hours) increases CAMP mRNA levels in keratinocytes.MHP (100 μM for 24 hours) increases CAMP protein levels in keratinocytes. TCell Viability Assay Cell Line:Keratinocytes Concentration:100 μM Incubation Time:24 hours Result:Increased CAMP protein levels in keratinocytes.
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体内实验——
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同义词Defensamide | methyl caprooyl tyrosinate | MHP
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通路Metabolic Enzyme/Protease
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靶点Phosphatase
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受体SphK
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研究领域——
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适应症——
化学信息
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CAS Number1104874-94-3
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分子量293.36
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分子式C16H23NO4
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 100 mg/mL 340.88 mM; H2O : < 0.1 mg/mL
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SMILESOc1ccc(C[C@H](NC(=O)CCCCC)C(=O)OC)cc1
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化学全称(S)-Methyl 2-(hexanamido)-3-(4-hydroxyphenyl)propanoate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Jeong SK, et al. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep;79(3):229-34.
产品手册
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