Caffeic Acid Phenethyl Ester

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Caffeic Acid Phenether (CAPE) 抑制核转录因子 NF-kappa B 的激活，并可能抑制 p70S6K 和 Akt 驱动的信号通路，具有抗肿瘤、细胞保护和免疫调节活性。

Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).

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CAPE | Caffeic Acid Phenethyl Ester | β-Phenylethyl Caffeate

Others

Other Targets

NF-κB

Inflammation/Immunology

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104594-70-9

284.31

C17H16O4

>98% (HPLC)

DMSO : 150 mg/mL. 527.59 mM;

c1ccc(cc1)CCOC(=O)/C=C/c1ccc(c(c1)O)O

2-Phenylethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

(-20℃)

With Ice Pack

≥ 2 years