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Alogliptin
CAS No. 850649-61-5
Alogliptin ( Alogliptin )
产品货号. M17613 CAS No. 850649-61-5
Alogliptin(SYR-322) 是一种有效的选择性 DPP-4 抑制剂，IC50 <10 nM，选择性比 DPP-8 和 DPP-9 高 10, 000 倍。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥89 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥94 | 有现货 |
|
生物学信息
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产品名称Alogliptin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Alogliptin(SYR-322) 是一种有效的选择性 DPP-4 抑制剂，IC50 <10 nM，选择性比 DPP-8 和 DPP-9 高 10, 000 倍。
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产品描述Alogliptin is a DPP-4 inhibitor used for the treatment of Type 2 diabetes. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.
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体外实验——
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体内实验——
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同义词Alogliptin
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通路Chromatin/Epigenetic
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靶点Sirtuin
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受体DPP-4
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研究领域Metabolic Disease
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适应症——
化学信息
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CAS Number850649-61-5
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分子量339.39
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分子式C18H21N5O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (294.65 mM)
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SMILESCN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC2=CC=CC=C2C#N)C1=O
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化学全称(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Feng J, et al. J Med Chem, 2007, 50(10), 2297-2300.
